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CCL2 has similar excitatory effects to TNF-α in a subgroup of inflamed C-fiber axons

Peripheral nerve inflammation can cause neuronal excitability changes that have been implicated in the pathogenesis of chronic pain. Although the neuroimmune interactions that lead to such physiological changes are unclear, in vitro studies suggest that the chemokine CCL2 may be involved. This in vi...

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Detalles Bibliográficos
Autores principales: Richards, Natalie, Batty, Thomas, Dilley, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234089/
https://www.ncbi.nlm.nih.gov/pubmed/21865436
http://dx.doi.org/10.1152/jn.00183.2011