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Maspin is a deoxycholate-inducible, anti-apoptotic stress-response protein differentially expressed during colon carcinogenesis

Increased maspin expression in the colon is related to colon cancer risk and patient survival. Maspin is induced by the hydrophobic bile acid, deoxycholate (DOC), which is an endogenous carcinogen and inducer of oxidative stress and DNA damage in the colon. Persistent exposure of colon epithelial ce...

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Detalles Bibliográficos
Autores principales: Payne, Claire M, Holubec, Hana, Crowley-Skillicorn, Cheray, Nguyen, Huy, Bernstein, Harris, Wilcox, George, Bernstein, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234125/
https://www.ncbi.nlm.nih.gov/pubmed/22162927
http://dx.doi.org/10.2147/CEG.S24093