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Azelnidipine prevents cardiac dysfunction in streptozotocin-diabetic rats by reducing intracellular calcium accumulation, oxidative stress and apoptosis

BACKGROUND: Numerous evidences suggest that diabetic heart is characterized by compromised ventricular contraction and prolonged relaxation attributable to multiple causative factors including calcium accumulation, oxidative stress and apoptosis. Therapeutic interventions to prevent calcium accumula...

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Detalles Bibliográficos
Autores principales: Kain, Vasundhara, Kumar, Sandeep, Sitasawad, Sandhya L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234183/
https://www.ncbi.nlm.nih.gov/pubmed/22054019
http://dx.doi.org/10.1186/1475-2840-10-97