Structural Insights into the Inhibition of Cytosolic 5′-Nucleotidase II (cN-II) by Ribonucleoside 5′-Monophosphate Analogues

Cytosolic 5′-nucleotidase II (cN-II) regulates the intracellular nucleotide pools within the cell by catalyzing the dephosphorylation of 6-hydroxypurine nucleoside 5′-monophosphates. Beside this physiological function, high level of cN-II expression is correlated with abnormal patient outcome when t...

Descripción completa

Detalles Bibliográficos
Autores principales: Gallier, Franck, Lallemand, Perrine, Meurillon, Maïa, Jordheim, Lars P., Dumontet, Charles, Périgaud, Christian, Lionne, Corinne, Peyrottes, Suzanne, Chaloin, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234209/
https://www.ncbi.nlm.nih.gov/pubmed/22174667
http://dx.doi.org/10.1371/journal.pcbi.1002295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234209/
https://www.ncbi.nlm.nih.gov/pubmed/22174667
http://dx.doi.org/10.1371/journal.pcbi.1002295

Ejemplares similares