Mining the LIPG Allelic Spectrum Reveals the Contribution of Rare and Common Regulatory Variants to HDL Cholesterol

Genome-wide association studies (GWAS) have successfully identified loci associated with quantitative traits, such as blood lipids. Deep resequencing studies are being utilized to catalogue the allelic spectrum at GWAS loci. The goal of these studies is to identify causative variants and missing her...

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Detalles Bibliográficos
Autores principales: Khetarpal, Sumeet A., Edmondson, Andrew C., Raghavan, Avanthi, Neeli, Hemanth, Jin, Weijun, Badellino, Karen O., Demissie, Serkalem, Manning, Alisa K., DerOhannessian, Stephanie L., Wolfe, Megan L., Cupples, L. Adrienne, Li, Mingyao, Kathiresan, Sekar, Rader, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234219/
https://www.ncbi.nlm.nih.gov/pubmed/22174694
http://dx.doi.org/10.1371/journal.pgen.1002393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234219/
https://www.ncbi.nlm.nih.gov/pubmed/22174694
http://dx.doi.org/10.1371/journal.pgen.1002393

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