Deficiency of a Niemann-Pick, Type C1-related Protein in Toxoplasma Is Associated with Multiple Lipidoses and Increased Pathogenicity

Several proteins that play key roles in cholesterol synthesis, regulation, trafficking and signaling are united by sharing the phylogenetically conserved ‘sterol-sensing domain’ (SSD). The intracellular parasite Toxoplasma possesses at least one gene coding for a protein containing the canonical SSD...

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Detalles Bibliográficos
Autores principales: Lige, Bao, Romano, Julia D., Bandaru, Veera Venkata Ratnam, Ehrenman, Karen, Levitskaya, Jelena, Sampels, Vera, Haughey, Norman J., Coppens, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234224/
https://www.ncbi.nlm.nih.gov/pubmed/22174676
http://dx.doi.org/10.1371/journal.ppat.1002410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234224/
https://www.ncbi.nlm.nih.gov/pubmed/22174676
http://dx.doi.org/10.1371/journal.ppat.1002410

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