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A Novel Role for the NLRC4 Inflammasome in Mucosal Defenses against the Fungal Pathogen Candida albicans

Candida sp. are opportunistic fungal pathogens that colonize the skin and oral cavity and, when overgrown under permissive conditions, cause inflammation and disease. Previously, we identified a central role for the NLRP3 inflammasome in regulating IL-1β production and resistance to dissemination fr...

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Detalles Bibliográficos
Autores principales: Tomalka, Jeffrey, Ganesan, Sandhya, Azodi, Elaheh, Patel, Krupen, Majmudar, Parth, Hall, Brian A., Fitzgerald, Katherine A., Hise, Amy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234225/
https://www.ncbi.nlm.nih.gov/pubmed/22174673
http://dx.doi.org/10.1371/journal.ppat.1002379