SAMHD1-Deficient CD14+ Cells from Individuals with Aicardi-Goutières Syndrome Are Highly Susceptible to HIV-1 Infection

Myeloid blood cells are largely resistant to infection with human immunodeficiency virus type 1 (HIV-1). Recently, it was reported that Vpx from HIV-2/SIVsm facilitates infection of these cells by counteracting the host restriction factor SAMHD1. Here, we independently confirmed that Vpx interacts w...

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Detalles Bibliográficos
Autores principales: Berger, André, Sommer, Andreas F. R., Zwarg, Jenny, Hamdorf, Matthias, Welzel, Karin, Esly, Nicole, Panitz, Sylvia, Reuter, Andreas, Ramos, Irene, Jatiani, Asavari, Mulder, Lubbertus C. F., Fernandez-Sesma, Ana, Rutsch, Frank, Simon, Viviana, König, Renate, Flory, Egbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234228/
https://www.ncbi.nlm.nih.gov/pubmed/22174685
http://dx.doi.org/10.1371/journal.ppat.1002425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234228/
https://www.ncbi.nlm.nih.gov/pubmed/22174685
http://dx.doi.org/10.1371/journal.ppat.1002425

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