Role of Permissive Neuraminidase Mutations in Influenza A/Brisbane/59/2007-like (H1N1) Viruses

Neuraminidase (NA) mutations conferring resistance to NA inhibitors were believed to compromise influenza virus fitness. Unexpectedly, an oseltamivir-resistant A/Brisbane/59/2007 (Bris07)-like H1N1 H275Y NA variant emerged in 2007 and completely replaced the wild-type (WT) strain in 2008–2009. The N...

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Detalles Bibliográficos
Autores principales: Abed, Yacine, Pizzorno, Andrés, Bouhy, Xavier, Boivin, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234239/
https://www.ncbi.nlm.nih.gov/pubmed/22174688
http://dx.doi.org/10.1371/journal.ppat.1002431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234239/
https://www.ncbi.nlm.nih.gov/pubmed/22174688
http://dx.doi.org/10.1371/journal.ppat.1002431

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