Involvement of Activation of PKR in HBx-siRNA-Mediated Innate Immune Effects on HBV Inhibition

RNA interference (RNAi) of virus-specific genes offers the possibility of developing a new anti-hepatitis B virus (anti-HBV) therapy. Recent studies have revealed that siRNAs can induce an innate immune response in vitro and in vivo. Here, HBVx (HBx) mRNA expression and HBV replication were signific...

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Detalles Bibliográficos
Autores principales: Han, Qiuju, Zhang, Cai, Zhang, Jian, Tian, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234243/
https://www.ncbi.nlm.nih.gov/pubmed/22174754
http://dx.doi.org/10.1371/journal.pone.0027931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234243/
https://www.ncbi.nlm.nih.gov/pubmed/22174754
http://dx.doi.org/10.1371/journal.pone.0027931

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