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Involvement of Activation of PKR in HBx-siRNA-Mediated Innate Immune Effects on HBV Inhibition
RNA interference (RNAi) of virus-specific genes offers the possibility of developing a new anti-hepatitis B virus (anti-HBV) therapy. Recent studies have revealed that siRNAs can induce an innate immune response in vitro and in vivo. Here, HBVx (HBx) mRNA expression and HBV replication were signific...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234243/ https://www.ncbi.nlm.nih.gov/pubmed/22174754 http://dx.doi.org/10.1371/journal.pone.0027931 |