Tau-Targeted Immunization Impedes Progression of Neurofibrillary Histopathology in Aged P301L Tau Transgenic Mice

In Alzheimer's disease (AD) brains, the microtubule-associated protein tau and amyloid-β (Aβ) deposit as intracellular neurofibrillary tangles (NFTs) and extracellular plaques, respectively. Tau deposits are furthermore found in a significant number of frontotemporal dementia cases. These disea...

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Detalles Bibliográficos
Autores principales: Bi, Mian, Ittner, Arne, Ke, Yazi D., Götz, Jürgen, Ittner, Lars M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234245/
https://www.ncbi.nlm.nih.gov/pubmed/22174735
http://dx.doi.org/10.1371/journal.pone.0026860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234245/
https://www.ncbi.nlm.nih.gov/pubmed/22174735
http://dx.doi.org/10.1371/journal.pone.0026860

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