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The Human Cytomegalovirus UL11 Protein Interacts with the Receptor Tyrosine Phosphatase CD45, Resulting in Functional Paralysis of T Cells

Human cytomegalovirus (CMV) exerts diverse and complex effects on the immune system, not all of which have been attributed to viral genes. Acute CMV infection results in transient restrictions in T cell proliferative ability, which can impair the control of the virus and increase the risk of seconda...

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Detalles Bibliográficos
Autores principales: Gabaev, Ildar, Steinbrück, Lars, Pokoyski, Claudia, Pich, Andreas, Stanton, Richard J., Schwinzer, Reinhard, Schulz, Thomas F., Jacobs, Roland, Messerle, Martin, Kay-Fedorov, Penelope C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234252/
https://www.ncbi.nlm.nih.gov/pubmed/22174689
http://dx.doi.org/10.1371/journal.ppat.1002432