Cargando…

Skeletal Muscle-Specific Expression of PGC-1α-b, an Exercise-Responsive Isoform, Increases Exercise Capacity and Peak Oxygen Uptake

BACKGROUND: Maximal oxygen uptake (VO(2max)) predicts mortality and is associated with endurance performance. Trained subjects have a high VO(2max) due to a high cardiac output and high metabolic capacity of skeletal muscles. Peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), a nu...

Descripción completa

Detalles Bibliográficos
Autores principales: Tadaishi, Miki, Miura, Shinji, Kai, Yuko, Kano, Yutaka, Oishi, Yuichi, Ezaki, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234261/
https://www.ncbi.nlm.nih.gov/pubmed/22174785
http://dx.doi.org/10.1371/journal.pone.0028290