Possible Down Regulation of the p16 Gene Promoter in Individuals with Hepatocellular Carcinoma

BACKGROUND: The p16 tumor suppressor gene is an important negative regulator of the cell cycle. Inactivation of p16, especially via promoter hypermethylation, has been found in numerous human cancers such as breast, lung, colorectal, and liver. OBJECTIVES: To determine the role of epigenetic methyla...

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Detalles Bibliográficos
Autores principales: Shiraz, Oranous Bashti, Galehdari, Hamid, Yavarian, Majid, Geramizadeh, Bita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234541/
https://www.ncbi.nlm.nih.gov/pubmed/22235214
http://dx.doi.org/10.5812/kowsar.1735143X.732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234541/
https://www.ncbi.nlm.nih.gov/pubmed/22235214
http://dx.doi.org/10.5812/kowsar.1735143X.732

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