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Possible Down Regulation of the p16 Gene Promoter in Individuals with Hepatocellular Carcinoma
BACKGROUND: The p16 tumor suppressor gene is an important negative regulator of the cell cycle. Inactivation of p16, especially via promoter hypermethylation, has been found in numerous human cancers such as breast, lung, colorectal, and liver. OBJECTIVES: To determine the role of epigenetic methyla...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Kowsar
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234541/ https://www.ncbi.nlm.nih.gov/pubmed/22235214 http://dx.doi.org/10.5812/kowsar.1735143X.732 |