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Two Panels of Steroid Receptor Luciferase Reporter Cell Lines for Compound Profiling

Steroid hormone receptors represent a major target in drug discovery. As ligand inducible transcription factors, their activity can be modulated by small lipophilic molecules. Here we describe two panels of potent and selective luciferase reporter cell lines based on cells with low endogenous steroi...

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Detalles Bibliográficos
Autores principales: Sedlák, David, Paguio, Aileen, Bartůněk, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234597/
https://www.ncbi.nlm.nih.gov/pubmed/21375502
http://dx.doi.org/10.2174/138620711795222446