N,N’-Bis(2-chloroethyl)-N-nitrosourea (BCNU)-induced Apoptosis of Neural Progenitor Cells in the Developing Fetal Rat Brain

N,N’-bis(2-chloroethyl)-N-nitrosourea (BCNU) is one of the major drugs used in chemotherapy against malignant gliomas due to its effects, such as induction of bifunctional alkylation of DNA and formation of interstrand DNA cross-linkages, and induces cortical malformations in the fetal and neonatal...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Tsuyoshi, Kanemitsu, Hiroyuki, Yamamoto, Satoshi, Komatsu, Masahiko, Uemura, Hiroyuki, Tamura, Kazutoshi, Shirai, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Toxicologic Pathology 2010
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234648/
https://www.ncbi.nlm.nih.gov/pubmed/22272008
http://dx.doi.org/10.1293/tox.23.25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234648/
https://www.ncbi.nlm.nih.gov/pubmed/22272008
http://dx.doi.org/10.1293/tox.23.25

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