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Evaluation of Short-term Myelotoxicity Study in Dietary Reduced Rats

This study attempted to prove our hypothesis that a short-term toxicity study, using a 4-day dosing regimen as an example, is suitable for evaluating myelotoxicity in rats. We compared the hematological, bone marrow cytological and histopathological results of 5-fluorouracil (5-FU) treated and pair-...

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Detalles Bibliográficos
Autores principales: Asanuma, Fumiko, Miyata, Hiroto, Iwaki, Yoshinobu, Kimura, Masaaki, Matsumoto, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Toxicologic Pathology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234654/
https://www.ncbi.nlm.nih.gov/pubmed/22272009
http://dx.doi.org/10.1293/tox.23.31