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Methionine Oxidation of Sup35 Protein Induces Formation of the [PSI(+)] Prion in a Yeast Peroxiredoxin Mutant

The frequency with which the yeast [PSI(+)] prion form of Sup35 arises de novo is controlled by a number of genetic and environmental factors. We have previously shown that in cells lacking the antioxidant peroxiredoxin proteins Tsa1 and Tsa2, the frequency of de novo formation of [PSI(+)] is greatl...

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Detalles Bibliográficos
Autores principales: Sideri, Theodora C., Koloteva-Levine, Nadejda, Tuite, Mick F., Grant, Chris M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234717/
https://www.ncbi.nlm.nih.gov/pubmed/21832086
http://dx.doi.org/10.1074/jbc.M111.272419