Inhibitory Member of the Apoptosis-stimulating Proteins of the p53 Family (iASPP) Interacts with Protein Phosphatase 1 via a Noncanonical Binding Motif

Although kinase mutations have been identified in various human diseases, much less is known about protein phosphatases. Here, we show that all apoptosis-stimulating proteins of p53 (ASPP) family members can bind protein phosphatase 1 (PP1) via two distinct interacting motifs. ASPP2 interacts with P...

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Detalles Bibliográficos
Autores principales: Llanos, Susana, Royer, Christophe, Lu, Min, Bergamaschi, Daniele, Lee, Wen Hwa, Lu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234852/
https://www.ncbi.nlm.nih.gov/pubmed/21998301
http://dx.doi.org/10.1074/jbc.M111.270751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234852/
https://www.ncbi.nlm.nih.gov/pubmed/21998301
http://dx.doi.org/10.1074/jbc.M111.270751

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