The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR): THREE-DIMENSIONAL STRUCTURE AND LOCALIZATION OF A CHANNEL GATE

Cystic fibrosis affects about 1 in 2500 live births and involves loss of transmembrane chloride flux due to a lack of a membrane protein channel termed the cystic fibrosis transmembrane conductance regulator (CFTR). We have studied CFTR structure by electron crystallography. The data were compared w...

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Detalles Bibliográficos
Autores principales: Rosenberg, Mark F., O'Ryan, Liam P., Hughes, Guy, Zhao, Zhefeng, Aleksandrov, Luba A., Riordan, John R., Ford, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234965/
https://www.ncbi.nlm.nih.gov/pubmed/21931164
http://dx.doi.org/10.1074/jbc.M111.292268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234965/
https://www.ncbi.nlm.nih.gov/pubmed/21931164
http://dx.doi.org/10.1074/jbc.M111.292268

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