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The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR): THREE-DIMENSIONAL STRUCTURE AND LOCALIZATION OF A CHANNEL GATE

Cystic fibrosis affects about 1 in 2500 live births and involves loss of transmembrane chloride flux due to a lack of a membrane protein channel termed the cystic fibrosis transmembrane conductance regulator (CFTR). We have studied CFTR structure by electron crystallography. The data were compared w...

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Detalles Bibliográficos
Autores principales:	Rosenberg, Mark F., O'Ryan, Liam P., Hughes, Guy, Zhao, Zhefeng, Aleksandrov, Luba A., Riordan, John R., Ford, Robert C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2011
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234965/ https://www.ncbi.nlm.nih.gov/pubmed/21931164 http://dx.doi.org/10.1074/jbc.M111.292268

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