Methylation of L1Hs promoters is lower on the inactive X, has a tendency of being higher on autosomes in smaller genomes and shows inter-individual variability at some loci

LINE-1 repeats account for ∼17% of the human genome. Little is known about their individual methylation patterns, because their repetitive, almost identical sequences make them difficult to be individually targeted. Here, we used bisulfite conversion to study methylation at individual LINE-1 repeats...

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Detalles Bibliográficos
Autores principales: Singer, Heike, Walier, Maja, Nüsgen, Nicole, Meesters, Christian, Schreiner, Felix, Woelfle, Joachim, Fimmers, Rolf, Wienker, Thomas, Kalscheuer, Vera M., Becker, Tim, Schwaab, Rainer, Oldenburg, Johannes, El-Maarri, Osman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235015/
https://www.ncbi.nlm.nih.gov/pubmed/21972244
http://dx.doi.org/10.1093/hmg/ddr456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235015/
https://www.ncbi.nlm.nih.gov/pubmed/21972244
http://dx.doi.org/10.1093/hmg/ddr456

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