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Novel mucus-penetrating liposomes as a potential oral drug delivery system: preparation, in vitro characterization, and enhanced cellular uptake

BACKGROUND: The aim of this study was to investigate the intestinal mucus-penetrating properties and intestinal cellular uptake of two types of liposomes modified by Pluronic F127 (PF127). METHODS: The two types of liposomes, ie, PF127-inlaid liposomes and PF127-adsorbed liposomes, were prepared by...

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Detalles Bibliográficos
Autores principales: Li, Xiuying, Chen, Dan, Le, Chaoyi, Zhu, Chunliu, Gan, Yong, Hovgaard, Lars, Yang, Mingshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235033/
https://www.ncbi.nlm.nih.gov/pubmed/22163166
http://dx.doi.org/10.2147/IJN.S25741