Tetradecylthioacetic acid inhibits proliferation of human SW620 colon cancer cells - gene expression profiling implies endoplasmic reticulum stress

BACKGROUND: Previous reports have shown an antiproliferative effect of the synthetic, 3-thia fatty acid tetradecylthioacetic acid (TTA) on different cancer cells in vitro and in vivo. The mechanisms behind the observed effects are poorly understood. We therefore wanted to explore the molecular mecha...

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Detalles Bibliográficos
Autores principales: Lundemo, Anne G, Pettersen, Caroline HH, Berge, Kjetil, Berge, Rolf K, Schønberg, Svanhild A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235040/
https://www.ncbi.nlm.nih.gov/pubmed/22027281
http://dx.doi.org/10.1186/1476-511X-10-190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235040/
https://www.ncbi.nlm.nih.gov/pubmed/22027281
http://dx.doi.org/10.1186/1476-511X-10-190

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