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Spatial and temporal genetic heterogeneity of epidermal growth factor receptor gene status in a patient with non-small cell lung cancer: a case report

INTRODUCTION: To date, an epidermal growth factor receptor-activating mutation is recognized as a genetic hallmark that predicts a good response to treatment with epidermal growth factor receptor tyrosine kinase inhibitor. However, there has been less long-term observation of the mutational status w...

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Detalles Bibliográficos
Autores principales: Ogata, Makoto, Shimizu, Toshiki, Yokoi, Takashi, Nomura, Shosaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235080/
https://www.ncbi.nlm.nih.gov/pubmed/22108465
http://dx.doi.org/10.1186/1752-1947-5-553