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Spatial and temporal genetic heterogeneity of epidermal growth factor receptor gene status in a patient with non-small cell lung cancer: a case report
INTRODUCTION: To date, an epidermal growth factor receptor-activating mutation is recognized as a genetic hallmark that predicts a good response to treatment with epidermal growth factor receptor tyrosine kinase inhibitor. However, there has been less long-term observation of the mutational status w...
Autores principales: | Ogata, Makoto, Shimizu, Toshiki, Yokoi, Takashi, Nomura, Shosaku |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235080/ https://www.ncbi.nlm.nih.gov/pubmed/22108465 http://dx.doi.org/10.1186/1752-1947-5-553 |
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