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Deriving Mechanisms Responsible for the Lack of Correlation between Hypoxia and Acidity in Solid Tumors
Hypoxia and acidity are two main microenvironmental factors intimately associated with solid tumors and play critical roles in tumor growth and metastasis. The experimental results of Helmlinger and colleagues (Nature Medicine 3, 177, 1997) provide evidence of a lack of correlation between these fac...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235095/ https://www.ncbi.nlm.nih.gov/pubmed/22174768 http://dx.doi.org/10.1371/journal.pone.0028101 |