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Deriving Mechanisms Responsible for the Lack of Correlation between Hypoxia and Acidity in Solid Tumors

Hypoxia and acidity are two main microenvironmental factors intimately associated with solid tumors and play critical roles in tumor growth and metastasis. The experimental results of Helmlinger and colleagues (Nature Medicine 3, 177, 1997) provide evidence of a lack of correlation between these fac...

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Detalles Bibliográficos
Autores principales: Molavian, Hamid R., Kohandel, Mohammad, Milosevic, Michael, Sivaloganathan, Sivabal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235095/
https://www.ncbi.nlm.nih.gov/pubmed/22174768
http://dx.doi.org/10.1371/journal.pone.0028101