Modulation of Phosducin-Like Protein 3 (PhLP3) Levels Promotes Cytoskeletal Remodelling in a MAPK and RhoA-Dependent Manner

BACKGROUND: Phosducin-like protein 3 (PhLP3) forms a ternary complex with the ATP-dependent molecular chaperone CCT and its folding client tubulin. In vitro studies suggest PhLP3 plays an inhibitory role in β-tubulin folding while conversely in vivo genetic studies suggest PhLP3 is required for the...

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Detalles Bibliográficos
Autores principales: Hayes, Nandini V. L., Jossé, Lyne, Smales, C. Mark, Carden, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235111/
https://www.ncbi.nlm.nih.gov/pubmed/22174782
http://dx.doi.org/10.1371/journal.pone.0028271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235111/
https://www.ncbi.nlm.nih.gov/pubmed/22174782
http://dx.doi.org/10.1371/journal.pone.0028271

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