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Oleanolic Acid Initiates Apoptosis in Non-Small Cell Lung Cancer Cell Lines and Reduces Metastasis of a B16F10 Melanoma Model In Vivo

BACKGROUND: Drug resistance, a process mediated by multiple mechanisms, is a critical determinant for treating lung cancer. The aim of this study is to determine if oleanolic acid (OA), a pentacyclic triterpene present in several plants, is able to circumvent the mechanisms of drug resistance presen...

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Detalles Bibliográficos
Autores principales: Lúcio, Kelly Araújo, Rocha, Gleice da Graça, Monção-Ribeiro, Leonardo Campos, Fernandes, Janaina, Takiya, Christina Maeda, Gattass, Cerli Rocha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235133/
https://www.ncbi.nlm.nih.gov/pubmed/22174843
http://dx.doi.org/10.1371/journal.pone.0028596