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Oleanolic Acid Initiates Apoptosis in Non-Small Cell Lung Cancer Cell Lines and Reduces Metastasis of a B16F10 Melanoma Model In Vivo
BACKGROUND: Drug resistance, a process mediated by multiple mechanisms, is a critical determinant for treating lung cancer. The aim of this study is to determine if oleanolic acid (OA), a pentacyclic triterpene present in several plants, is able to circumvent the mechanisms of drug resistance presen...
Autores principales: | Lúcio, Kelly Araújo, Rocha, Gleice da Graça, Monção-Ribeiro, Leonardo Campos, Fernandes, Janaina, Takiya, Christina Maeda, Gattass, Cerli Rocha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235133/ https://www.ncbi.nlm.nih.gov/pubmed/22174843 http://dx.doi.org/10.1371/journal.pone.0028596 |
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