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Antitumor Activity of Sorafenib in Human Cancer Cell Lines with Acquired Resistance to EGFR and VEGFR Tyrosine Kinase Inhibitors

Treatment of non small cell lung cancer (NSCLC) and colorectal cancer (CRC) have substantially changed in the last years with the introduction of epidermal growth factor receptor (EGFR) inhibitors in the clinical practice. The understanding of mechanisms which regulate cells sensitivity to these dru...

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Detalles Bibliográficos
Autores principales: Morgillo, Floriana, Martinelli, Erika, Troiani, Teresa, Orditura, Michele, De Vita, Ferdinando, Ciardiello, Fortunato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235154/
https://www.ncbi.nlm.nih.gov/pubmed/22174910
http://dx.doi.org/10.1371/journal.pone.0028841