Efficient Conversion of Astrocytes to Functional Midbrain Dopaminergic Neurons Using a Single Polycistronic Vector

Direct cellular reprogramming is a powerful new tool for regenerative medicine. In efforts to understand and treat Parkinson's Disease (PD), which is marked by the degeneration of dopaminergic neurons in the midbrain, direct reprogramming provides a valuable new source of these cells. Astrocyte...

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Detalles Bibliográficos
Autores principales: Addis, Russell C., Hsu, Fu-Chun, Wright, Rebecca L., Dichter, Marc A., Coulter, Douglas A., Gearhart, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235158/
https://www.ncbi.nlm.nih.gov/pubmed/22174877
http://dx.doi.org/10.1371/journal.pone.0028719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235158/
https://www.ncbi.nlm.nih.gov/pubmed/22174877
http://dx.doi.org/10.1371/journal.pone.0028719

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