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Erroneous attribution of relevant transcription factor binding sites despite successful prediction of cis-regulatory modules

BACKGROUND: Cis-regulatory modules are bound by transcription factors to regulate gene expression. Characterizing these DNA sequences is central to understanding gene regulatory networks and gaining insight into mechanisms of transcriptional regulation, but genome-scale regulatory module discovery r...

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Detalles Bibliográficos
Autores principales: Halfon, Marc S, Zhu, Qianqian, Brennan, Elizabeth R, Zhou, Yiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235160/
https://www.ncbi.nlm.nih.gov/pubmed/22115527
http://dx.doi.org/10.1186/1471-2164-12-578