Activation of the Alternative NFκB Pathway Improves Disease Symptoms in a Model of Sjogren's Syndrome

The purpose of our study was to understand if Toll-like receptor 9 (TLR9) activation could contribute to the control of inflammation in Sjogren's syndrome. To this end, we manipulated TLR9 signaling in non-obese diabetic (NOD) and TLR9(−/−) mice using agonistic CpG oligonucleotide aptamers, TLR...

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Detalles Bibliográficos
Autores principales: Gilboa-Geffen, Adi, Wolf, Yochai, Hanin, Geula, Melamed-Book, Naomi, Pick, Marjorie, Bennett, Estelle R., Greenberg, David S., Lester, Susan, Rischmueller, Maureen, Soreq, Hermona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235165/
https://www.ncbi.nlm.nih.gov/pubmed/22174879
http://dx.doi.org/10.1371/journal.pone.0028727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235165/
https://www.ncbi.nlm.nih.gov/pubmed/22174879
http://dx.doi.org/10.1371/journal.pone.0028727

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