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Activation of the Alternative NFκB Pathway Improves Disease Symptoms in a Model of Sjogren's Syndrome
The purpose of our study was to understand if Toll-like receptor 9 (TLR9) activation could contribute to the control of inflammation in Sjogren's syndrome. To this end, we manipulated TLR9 signaling in non-obese diabetic (NOD) and TLR9(−/−) mice using agonistic CpG oligonucleotide aptamers, TLR...
Autores principales: | Gilboa-Geffen, Adi, Wolf, Yochai, Hanin, Geula, Melamed-Book, Naomi, Pick, Marjorie, Bennett, Estelle R., Greenberg, David S., Lester, Susan, Rischmueller, Maureen, Soreq, Hermona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235165/ https://www.ncbi.nlm.nih.gov/pubmed/22174879 http://dx.doi.org/10.1371/journal.pone.0028727 |
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