Rosiglitazone Inhibits Transforming Growth Factor-β1 Mediated Fibrogenesis in ADPKD Cyst-Lining Epithelial Cells

BACKGROUND: Interstitial fibrosis plays an important role in progressive renal dysfunction in autosomal dominant polycystic kidney disease (ADPKD). In our previous studies, we confirmed that PPAR-γ agonist, rosiglitazone could protect renal function and prolong the survival of a slowly progressive A...

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Detalles Bibliográficos
Autores principales: Liu, Yawei, Dai, Bing, Xu, Chenggang, Fu, Lili, Hua, Zhenhao, Mei, Changlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235173/
https://www.ncbi.nlm.nih.gov/pubmed/22174924
http://dx.doi.org/10.1371/journal.pone.0028915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235173/
https://www.ncbi.nlm.nih.gov/pubmed/22174924
http://dx.doi.org/10.1371/journal.pone.0028915

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