Cargando…
Rosiglitazone Inhibits Transforming Growth Factor-β1 Mediated Fibrogenesis in ADPKD Cyst-Lining Epithelial Cells
BACKGROUND: Interstitial fibrosis plays an important role in progressive renal dysfunction in autosomal dominant polycystic kidney disease (ADPKD). In our previous studies, we confirmed that PPAR-γ agonist, rosiglitazone could protect renal function and prolong the survival of a slowly progressive A...
Autores principales: | Liu, Yawei, Dai, Bing, Xu, Chenggang, Fu, Lili, Hua, Zhenhao, Mei, Changlin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235173/ https://www.ncbi.nlm.nih.gov/pubmed/22174924 http://dx.doi.org/10.1371/journal.pone.0028915 |
Ejemplares similares
-
Multiple thyroid cysts as an extra-renal manifestation of ADPKD
por: Alejmi, Abdulfattah, et al.
Publicado: (2008) -
Troglitazone suppresses transforming growth factor beta-mediated fibrogenesis in retinal pigment epithelial cells
por: Cheng, Huey-Chuan, et al.
Publicado: (2008) -
Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD
por: de Almeida, Rita M. C., et al.
Publicado: (2016) -
Rapamycin Inhibits Transforming Growth Factor β1-Induced Fibrogenesis in Primary Human Lung Fibroblasts
por: Gao, Yu, et al.
Publicado: (2013) -
Pirfenidone inhibits transforming growth factor-β1-induced fibrogenesis by blocking nuclear translocation of Smads in human retinal pigment epithelial cell line ARPE-19
por: Choi, Kyungsun, et al.
Publicado: (2012)