c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression

Despite 35 years of clinical trials, there is little improvement in one-year survival rates for patients with metastatic melanoma, and the disease is essentially untreatable if not cured surgically. The paucity of chemotherapeutic agents that are effective for treating metastatic melanoma indicates...

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Detalles Bibliográficos
Autores principales: Ganguly, Sourik S., Fiore, Leann S., Sims, Jonathan T., Friend, J. Woodrow, Srinivasan, Divyamani, Thacker, Matthew A., Cibull, Michael L., Wang, Chi, Novak, Marian, Kaetzel, David M., Plattner, Rina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235241/
https://www.ncbi.nlm.nih.gov/pubmed/21892207
http://dx.doi.org/10.1038/onc.2011.361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235241/
https://www.ncbi.nlm.nih.gov/pubmed/21892207
http://dx.doi.org/10.1038/onc.2011.361

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