Imaging gene delivery in a mouse model of congenital neuronal ceroid lipofuscinosis

Adeno-associated virus (AAV) mediated gene replacement for lysosomal disorders have been spurred by the ability of some serotypes to efficiently transduce neurons in the brain and by the ability of lysosomal enzymes to cross-correct among cells. Here, we explored enzyme replacement therapy in a knoc...

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Detalles Bibliográficos
Autores principales: Pike, Lisa S., Tannous, Bakhos A., Deliolanis, Nikolaos C., Hsich, Gary, Morse, Danielle, Tung, Ching-Hsuan, Sena-Esteves, Miguel, Breakefield, Xandra O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235265/
https://www.ncbi.nlm.nih.gov/pubmed/21900963
http://dx.doi.org/10.1038/gt.2011.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235265/
https://www.ncbi.nlm.nih.gov/pubmed/21900963
http://dx.doi.org/10.1038/gt.2011.118

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