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Betaine Treatment Attenuates Chronic Ethanol-Induced Hepatic Steatosis and Alterations to the Mitochondrial Respiratory Chain Proteome

Introduction. Mitochondrial damage and disruption in oxidative phosphorylation contributes to the pathogenesis of alcoholic liver injury. Herein, we tested the hypothesis that the hepatoprotective actions of betaine against alcoholic liver injury occur at the level of the mitochondrial proteome. Met...

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Detalles Bibliográficos
Autores principales: Kharbanda, Kusum K., Todero, Sandra L., King, Adrienne L., Osna, Natalia A., McVicker, Benita L., Tuma, Dean J., Wisecarver, James L., Bailey, Shannon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235488/
https://www.ncbi.nlm.nih.gov/pubmed/22187660
http://dx.doi.org/10.1155/2012/962183