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Current Status of the Immunomodulation and Immunomediated Therapeutic Strategies for Multiple Sclerosis
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, and CD4(+) T cells form the core immunopathogenic cascade leading to chronic inflammation. Traditionally, Th1 cells (interferon-γ-producing CD4(+) T cells) driven by interleukin 12 (IL12) were considered to be the enceph...
Главные авторы: | , , , , , |
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Формат: | Online Статья Текст |
Язык: | English |
Опубликовано: |
Hindawi Publishing Corporation
2012
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Предметы: | |
Online-ссылка: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235500/ https://www.ncbi.nlm.nih.gov/pubmed/22203863 http://dx.doi.org/10.1155/2012/970789 |