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Current Status of the Immunomodulation and Immunomediated Therapeutic Strategies for Multiple Sclerosis

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, and CD4(+) T cells form the core immunopathogenic cascade leading to chronic inflammation. Traditionally, Th1 cells (interferon-γ-producing CD4(+) T cells) driven by interleukin 12 (IL12) were considered to be the enceph...

Полное описание

Библиографические подробности
Главные авторы: Chen, Shyi-Jou, Wang, Yen-Ling, Fan, Hueng-Chuen, Lo, Wen-Tsung, Wang, Chih-Chien, Sytwu, Huey-Kang
Формат: Online Статья Текст
Язык:English
Опубликовано: Hindawi Publishing Corporation 2012
Предметы:
Online-ссылка:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235500/
https://www.ncbi.nlm.nih.gov/pubmed/22203863
http://dx.doi.org/10.1155/2012/970789