Cargando…

Structural Basis for the Antiviral Activity of BST-2/Tetherin and Its Viral Antagonism

The interferon-inducible host restriction factor bone marrow stromal antigen 2 (BST-2/tetherin) blocks the release of HIV-1 and other enveloped viruses. In turn, these viruses have evolved specific antagonists to counteract this host antiviral molecule, such as the HIV-1 protein Vpu. BST-2 is a type...

Descripción completa

Detalles Bibliográficos
Autores principales: Arias, Juan F., Iwabu, Yukie, Tokunaga, Kenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235769/
https://www.ncbi.nlm.nih.gov/pubmed/22180752
http://dx.doi.org/10.3389/fmicb.2011.00250