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Structural Basis for the Antiviral Activity of BST-2/Tetherin and Its Viral Antagonism
The interferon-inducible host restriction factor bone marrow stromal antigen 2 (BST-2/tetherin) blocks the release of HIV-1 and other enveloped viruses. In turn, these viruses have evolved specific antagonists to counteract this host antiviral molecule, such as the HIV-1 protein Vpu. BST-2 is a type...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235769/ https://www.ncbi.nlm.nih.gov/pubmed/22180752 http://dx.doi.org/10.3389/fmicb.2011.00250 |