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BRAF in Melanoma: Pathogenesis, Diagnosis, Inhibition, and Resistance

Since the initial discovery that a subset of patients with cutaneous melanoma harbor BRAF mutations, substantial research has been focused on determining the pathologic consequences of BRAF mutations, optimizing diagnostic techniques to identify these mutations, and developing therapeutic interventi...

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Detalles Bibliográficos
Autores principales: Sullivan, Ryan J., Flaherty, Keith T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235817/
https://www.ncbi.nlm.nih.gov/pubmed/22175026
http://dx.doi.org/10.1155/2011/423239