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Drosophila insulin and target of rapamycin (TOR) pathways regulate GSK3 beta activity to control Myc stability and determine Myc expression in vivo

BACKGROUND: Genetic studies in Drosophila melanogaster reveal an important role for Myc in controlling growth. Similar studies have also shown how components of the insulin and target of rapamycin (TOR) pathways are key regulators of growth. Despite a few suggestions that Myc transcriptional activit...

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Detalles Bibliográficos
Autores principales: Parisi, Federica, Riccardo, Sara, Daniel, Margaret, Saqcena, Mahesh, Kundu, Nandini, Pession, Annalisa, Grifoni, Daniela, Stocker, Hugo, Tabak, Esteban, Bellosta, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235970/
https://www.ncbi.nlm.nih.gov/pubmed/21951762
http://dx.doi.org/10.1186/1741-7007-9-65