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Mapping the encounter state of a transient protein complex by PRE NMR spectroscopy

Many biomolecular interactions proceed via a short-lived encounter state, consisting of multiple, lowly-populated species invisible to most experimental techniques. Recent development of paramagnetic relaxation enhancement (PRE) nuclear magnetic resonance (NMR) spectroscopy has allowed to directly v...

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Detalles Bibliográficos
Autores principales: Volkov, Alexander N., Ubbink, Marcellus, van Nuland, Nico A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235994/
https://www.ncbi.nlm.nih.gov/pubmed/21049303
http://dx.doi.org/10.1007/s10858-010-9452-6