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Complement-Mediated Neutralization of Dengue Virus Requires Mannose-Binding Lectin

Mannose-binding lectin (MBL) is a key soluble pathogen recognition protein of the innate immune system that binds specific mannose-containing glycans on the surfaces of microbial agents and initiates complement activation via the lectin pathway. Prior studies showed that MBL-dependent activation of...

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Detalles Bibliográficos
Autores principales: Avirutnan, Panisadee, Hauhart, Richard E., Marovich, Mary A., Garred, Peter, Atkinson, John P., Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236064/
https://www.ncbi.nlm.nih.gov/pubmed/22167226
http://dx.doi.org/10.1128/mBio.00276-11