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Complement-Mediated Neutralization of Dengue Virus Requires Mannose-Binding Lectin
Mannose-binding lectin (MBL) is a key soluble pathogen recognition protein of the innate immune system that binds specific mannose-containing glycans on the surfaces of microbial agents and initiates complement activation via the lectin pathway. Prior studies showed that MBL-dependent activation of...
Autores principales: | Avirutnan, Panisadee, Hauhart, Richard E., Marovich, Mary A., Garred, Peter, Atkinson, John P., Diamond, Michael S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236064/ https://www.ncbi.nlm.nih.gov/pubmed/22167226 http://dx.doi.org/10.1128/mBio.00276-11 |
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