The Antidiabetic Drug Ciglitazone Induces High Grade Bladder Cancer Cells Apoptosis through the Up-Regulation of TRAIL

BACKGROUND: Ciglitazone belongs to the thiazolidinediones class of antidiabetic drug family and is a high-affinity ligand for the Peroxisome Proliferator-Activated Receptor γ (PPARγ). Apart from its antidiabetic activity, this molecule shows antineoplastic effectiveness in numerous cancer cell lines...

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Detalles Bibliográficos
Autores principales: Plissonnier, Marie-Laure, Fauconnet, Sylvie, Bittard, Hugues, Lascombe, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236187/
https://www.ncbi.nlm.nih.gov/pubmed/22174792
http://dx.doi.org/10.1371/journal.pone.0028354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236187/
https://www.ncbi.nlm.nih.gov/pubmed/22174792
http://dx.doi.org/10.1371/journal.pone.0028354

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